Omics in Clinical Practice: Genomics, Pharmacogenomics, Proteomics, and Transcriptomics in Clinical Research (Paperback)

Introduction. Part 1: Omics and Human Disease. Comparative Mitochondrial Proteomics: Perspective in Human Diseases. Studies of Complex Biological Systems with Applications to Molecular Medicine: The Need to Integrate Transcriptomic and Proteomic Approaches. Next Generation Sequencing in Cancer Research and Clinical Application. Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice. Part 2: Translational and Personalized Medicine. Clinical Proteomics and Omics Clues Useful in Translational Medicine Research. Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data. Part 3: Molecular and Genetic Markers. Pitfalls and Limitations in Translation from Biomarker Discovery to Clinical Utility in Predictive and Personalised Medicine. How Bioinformatics Influences Health Informatics: Usage of Biomolecular Sequences, Expression Profiles and Automated Microscopic Image Analyses for Clinical Needs and Public Health. Application of "Omics" to Prion Biomarker Discovery. Part 4: Omics and Pathogens. Insights from Genomics into Bacterial Pathogen Populations. High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins of a New Pathogen: The Dirty Genome Approach. Coronavirus Genomics and Bioinformatics Analysis. Part 5: Companion Diagnostics. Applications of Next-Generation Sequencing Technologies to Diagnostic Virology. Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture. Index.