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· 제목 : Chemical Epigenetics (Paperback) 
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 화학 > 임상화학
· ISBN : 9783030429843
· 쪽수 : 567쪽
· 출판일 : 2021-04-01
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 화학 > 임상화학
· ISBN : 9783030429843
· 쪽수 : 567쪽
· 출판일 : 2021-04-01
목차
Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery.- Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases.- Sirtuin Inhibitors and Activators.- Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors.- Lysine Methyltransferases and Their Inhibitors.- PRMT Inhibitors.- Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors.- Inhibitors of JmjC-Containing Histone Demethylases.- Chemical Compounds Targeting DNA Methylation and Hydroxymethylation.- Applied Biophysics for Bromodomain Drug Discovery.- Methyl-Readers and Inhibitors.- Altered Long Non-coding RNA Expression in Cancer: Potential Biomarkers and Therapeutic Targets? - Acetylation and Methylation in Asthma, COPD, and Lung Cancer.- Structure-Based Design ofEpigenetic Inhibitors.- Experimental Methodologies for Detection and Mapping of Epigenetic DNA Marks.- Advanced Assays in Epigenetics.
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