Inhibitors of the Ras Superfamily G-Proteins, Part B: Volume 34

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· 제목 : Inhibitors of the Ras Superfamily G-Proteins, Part B: Volume 34 (Hardcover)
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 생화학
· ISBN : 9780124201460
· 쪽수 : 280쪽
· 출판일 : 2013-11-25

Discovery of Small-Molecule Ras Inhibitors that Display Anti-Tumor Activity by Interfering with Ras?GTP-Effector Interaction
Fumi Shima, Yoko Yoshikawa, Shigeyuki Matsumoto and Tohru Kataoka
An Orthosteric Inhibitor of the RAS-SOS Interaction
Seth Nickerson, Stephen T. Joy, Paramjit S. Arora and Dafna Bar-Sagi
Conformation-Specific Inhibitors of Raf kinases
Xiaolun Wang and Kristin Schleicher
Inhibitors of the ERK Mitogen-activated Protein Kinase Cascade for Targeting RAS Mutant Cancers
Leanna Gentry, Ahmed A. Samatar and Channing J. Der
Inhibiting the RAS - PI3K Pathway in Cancer Therapy
Clare Sheridan and Julian Downward
The RalGEF/Ral Pathway: Evaluating an Intervention Opportunity for Ras Cancers
Jonathan M. Cooper, Brian O. Bodemann and Michael A. White
p21-Activated Kinase Inhibitors
Joachim Rudolph, James J. Crawford, Klaus P. Hoeflich, and Jonathan Chernoff
Recent Progress in Developing Small Molecule Inhibitors Designed to Interfere with Ras Membrane Association: Towards Inhibiting K-Ras and N-Ras Functions
Fuyuhiko Tamanoi and Jie Lu
Synthetic Lethal Genetic Screens in Ras Mutant Cancers
Bing Yu and Ji Luo