책 이미지

책 정보
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 유전학/유전체학
· ISBN : 9780387949444
· 쪽수 : 330쪽
· 출판일 : 1997-02-27
목차
I: Early human evolution.- Recent African origin of human mitochondrial DNA: Review of the evidence and current status of the hypothesis.- Lines of descent from mitochondrial Eve: An evolutionary look at coalescence.- Phylogeography of human mtDNA: An Amerindian perspective.- Population structure and modern human origins.- Distribution of pairwise differences in growing populations.- Branching and inference in population genetics.- Human demography and the time since mitochondrial Eve.- II: Molecular techniques and data analysis.- Molecular population genetics of a phenotypically monomorphic protein in Drosophila.- Estimation of the amount of DNA polymorphism and statistical tests of the neutral mutation hypothesis based on DNA polymorphism.- Computational methods for the coalescent.- Applications of Metropolis-Hastings genealogy sampling.- Estimating selection and mutation rates from a random field model for polymorphic sites.- The use of linkage disequilibrium for estimating the recombination fraction between a marker and a disease gene.- Theory and applications of RAPD-PCR: Mispriming.- III: Genealogy and population models.- The structured coalescent.- An ancestral recombination graph.- The effect of purifying selection on genealogies.- Hierarchical and mean-field stepping stone models.- A note on the stepping stone model with extinction and recolonization.- On the normal-selection model.- Branching processes and evolution.