Cell Culture and Upstream Processing (Paperback)

1. Cell Line Development and Culture Strategies: Future Prospects to Improve Yields 2. Use of DNA Insulator Elements and Scaffold / Matrix-Attached Regions for Enhanced Recombinant Protein Expression 3. Targeted Gene Insertion to Enhance Protein Production From Cell Lines 4. Recombinant Human IgG Production From Myeloma and Chinese Hamster Ovary Cells 5. Cell Culture Media Development: Customization of Animal Origin-Free Components and Supplements 6. Post-Translational Modification of Recombinant Proteins 7. Metabolic Engineering to Control Glycosylation 8. An Alternative Approach: Humanization of N-glycosylation Pathways in Yeast 9. Perfusion or Fed-Batch? A Matter of Perspective