Molecular Biology in Medicinal Chemistry (Hardcover)

MOLECULAR TARGETS
Cellular Assays in Drug Discovery
Gene Knockout Models
Reporter Gene Assay Systems for the Investigation of GPCRs
From the Human Genome to New Drugs: The Potential of Orphan GPCRs
SYNTHESIS
Stereoselective Synthesis with the Help of Recombinant Enzymes
Nucleic Acid Drugs
ANALYSIS
Recent Trends in Enantioseparation of Chiral Drugs
Affinity Chromatography
NMR-based Drug Discovery
13C- and 15N-Isotopic Labeling of Proteins
Antibody Fragments as Crystallization Enhancers
KINETICS, METABOLISM AND TOXICOLOGY
Pharmacogenetics: The Effect of Inherited Genetic Variation on Drug Disposition and Drug Response
Pharmacogenomics of Bioavaliability and Elimination
Toxicogenomics: Integration of New Molecular Biological Tools in Toxicology