Ligand Design for G Protein-Coupled Receptors (Hardcover)

GPCRs in the human genome GPCR Three-dimensional structures: from bovine rhodopsin to homology models Orphan GPCRs and ligand design GPCR databases: From genes to proteins, from proteins to ligands Druggability of human GPCRs Molecular Mechanisms of GPCR activation & Oligomerisation Allosteric regulation of GPCRs Ligand-Based rational design Receptor-based rational design Chemogenomics approaches to ligand design and target priorisation GPCR targeted libraries and privileged structures