The Biochemistry of Drug Metabolism: Volume 1: Principles, Redox Reactions, Hydrolyses (Paperback)

Part 1: Principles and Overview
1.1. Drugs and Xenobiotics
1.2. What Are Drug Disposition and Metabolism?
1.3. Where Does Drug Metabolism Occur?
1.4. Consequences of Drug Metabolism -
An Overview
1.5. Drug Metabolism and Drug Discovery

Part 2: Redox Reactions and Their Enzymes
2.1. Cytochromes P450 (CYPs) and Flavin-Containing Monooxygenases (FMOs)
2.2. CYP-Catalyzed sp3-C-Oxidations
2.2. CYP-Catalyzed sp2-C- and sp-C-Oxidations
2.4. Oxidations of N- and S-Atoms Catalyzed by CYPs and/or FMOs
2.5. Other Reactions Catalyzed by CYPs
2.6. Other Oxidoreductases and Their Reactions

Part 3: Reactions of Hydrolysis and Their Enzymes
3.1. A Survey of Hydrolases
3.2. The Hydrolysis of Carboxylic Esters
3.3. Synthetic Reactions of Esterases
3.4. The Hydrolysis of Amides and Peptides
3.5. Hydrolytic Ring Opening
3.6. The Hydrolysis of Esters of Inorganic Acids
3.7. The Hydration of Epoxides
3.8. Miscellaneous Reactions